Cross-linking

Cross linking: a comprehensive overview

What is cross linking?

Cross-linking, also known as “cross-linking”, is an innovative treatment used to treat keratoconus, a condition in which the shape of the cornea (the clear window at the front of the eye) distorts and tapers into a cone shape.

The treatment is based on creating new chemical bonds between the collagen fibers in the cornea, thus strengthening it and slowing the progression of keratoconus.

When is cross-linking recommended?

Cross linking is recommended in the following cases:

Keratoconus diagnosis: When keratoconus is diagnosed, cross-linking can stop or slow down the progression of the disease and prevent further vision loss.
Advanced keratoconus: In cases of advanced keratoconus, cross-linking can avoid the need for corneal transplant surgery.
Frequent changes in glasses or contact lenses: When frequent changes in glasses or contact lenses are required due to keratoconus, cross-linking can stabilize vision and reduce the need for frequent changes.
Depletion of the cornea: in cases of depletion of the cornea, cross-linking can strengthen the cornea and prevent the progression of the depletion.

How is cross linking done?

The treatment is carried out in the ophthalmologist’s office, without the need for hospitalization.

The main steps are:

Numbing the eye: special anesthetic drops are inserted into the eye to numb it.
Removal of the epithelial layer: the epithelial layer, the outer layer of the cornea, is removed using alcohol.
Insertion of riboflavin: riboflavin, vitamin B2, is inserted into the cornea using special drops.
Ultraviolet light irradiation: Ultraviolet light rays are directed at the cornea to activate the riboflavin and create crosslinks between the collagen fibers.
Washing the eye: The eye is washed thoroughly to remove the riboflavin and other substances.
The eye bandage: a special bandage is placed on the eye to protect it after the treatment.

What is expected after cross linking?

Most people experience mild eye discomfort after treatment, such as burning, excessive tearing, and redness. These symptoms usually pass within a few days.

It is important to follow the ophthalmologist’s instructions after the treatment, and to attend regular follow-ups to make sure that the treatment is progressing properly.

Advantages of cross linking:

Non-invasive treatment: cross-linking is not surgery, and does not involve incisions or stitches.
Effectiveness: Studies show that cross-linking is effective in stopping or slowing the progression of keratoconus.
Safety: Cross linking is considered a relatively safe treatment, with rare side effects.
Improving vision: In some cases, cross-linking can even improve vision.